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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Adrenaline (epinephrine)

3

XII.e Takotsubo (stress) cardiomyopathy

1
Last update : 08/08/2012
 
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1
Drug and radiation history
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Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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Publications

[Reverse Takotsubo cardiomyopathy after iatrogenic epinephrine injection requiring percutaneous extracorporeal membrane oxygenation].
Canadian journal of anaesthesia = Journal canadien d'anesthesie 2014 Dec;61;1093-7 2014 Dec
Reverse Takotsubo cardiomyopathy in the setting of anaphylaxis treated with high-dose intravenous epinephrine.
The Journal of emergency medicine 2013 Jan;44;96-9 2013 Jan
Iatrogenic inverted Takotsubo syndrome following intravenous adrenaline injections for an allergic reaction.
International journal of cardiology 2013 Apr 30;165;e3-5 2013 Apr 30
Delayed takotsubo cardiomyopathy caused by excessive exogenous epinephrine administration after the treatment of angioedema.
Proceedings (Baylor University. Medical Center) 2012 Jul;25;229-30 2012 Jul
Inverted takotsubo cardiomyopathy secondary to adrenaline injection.
British journal of hospital medicine (London, England : 2005) 2011 Nov;72;646-7 2011 Nov
Reversible left ventricular dysfunction resembling Takotsubo syndrome after self-injection of adrenaline.
The Canadian journal of cardiology 2009 Jul;25;e261-2 2009 Jul
Iatrogenic Tako-Tsubo cardiomyopathy.
International journal of cardiology 2008 Mar 28;125;e16-8 2008 Mar 28

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