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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Heroin (intravenous)

5

IV.f Severe or catastrophic bronchospasm or asthma attack (can be fatal)

2
Last update : 18/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Heroin (inhaled, insufflated, snorted)
4
Methadone
5
Opiates - Opioids - Opium
5

Publications

Life-threatening asthma after heroin inhalation. A case report and a review of the literature.
Acta bio-medica : Atenei Parmensis 2010 Dec;81;63-7 2010 Dec
Inhaled heroin causing a life-threatening asthma exacerbation and marked peripheral eosinophilia.
British journal of hospital medicine (London, England : 2005) 2007 Jun;68;332-3 2007 Jun
The effects of cocaine and heroin use on intubation rates and hospital utilization in patients with acute asthma exacerbations.
Chest 2005 Oct;128;1951-7 2005 Oct
Heroin insufflation as a trigger for patients with life-threatening asthma.
Chest 2003 Feb;123;510-7 2003 Feb

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