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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Heroin (intravenous)

5

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

1
Last update : 09/10/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Heroin (inhaled, insufflated, snorted)
4
Methadone
5
Opiates - Opioids - Opium
5

Publications

Pulmonary hemorrhage in acute heroin overdose: a report of two cases.
Emergency radiology 2017 Dec;24;709-712 2017 Dec
Pulmonary edema in fatal heroin overdose: immunohistological investigations with IgE, collagen IV and laminin - no increase of defects of alveolar-capillary membranes.
Forensic science international 2000 May 15;110;87-96 2000 May 15

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