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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ibuprofen

3

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 07/09/2012
 
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Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Nonsteroidal anti-inflammatory drugs (NSAIDs)
5

Publications

Nonsteroidal anti-inflammatory drug hypersensitivity in a pediatric severe asthmatic population.
Pediatric pulmonology 2023 Oct;58;2983-2986 2023 Oct
Risk of acute exacerbation between acetaminophen and ibuprofen in children with asthma.
PeerJ 2019;7;e6760 2019
Short-term ibuprofen treatment and pulmonary function in children with asthma.
Indian pediatrics 2015 Aug;52;691-3 2015 Aug
How safe is ibuprofen in febrile asthmatic children?
Archives of disease in childhood 2004 Sep;89;885-6 2004 Sep
Asthma death induced by ibuprofen.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 1995 Aug;50;276-8 1995 Aug

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