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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Insulin

2

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 23/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Acute pulmonary edema caused by hypoglycemia due to insulin overdose.
Internal medicine (Tokyo, Japan) 2004 Nov;43;1056-9 2004 Nov
Hypoglycemia, a cause of pulmonary edema. Progressive, fatal pulmonary edema complicating hypoglycemia induced by alcohol and insulin.
Journal of the National Medical Association 1975 May;67;200-4 1975 May
Death due to treatment.
Proceedings of the Royal Society of Medicine 1953 Jan;46;13-20 1953 Jan

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