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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amiodarone

5

I.z An area or areas of consolidation

3
Last update : 09/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Dronedarone
2
Excipients-Vehicle-Preservatives (of drugs)
5
Thyroid hormones (exogenous)
1

Publications

Ultra-short course of low-dose amiodarone-induced post-operative fatal pulmonary toxicity.
The Journal of the Association of Physicians of India 2011 Jul;59;443-7 2011 Jul
Recurrent amiodarone pulmonary toxicity.
Southern medical journal 1996 Jan;89;85-6 1996 Jan

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