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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amiodarone

5

XV.o Path: Endogenous lipoid pneumonia (phospholipidosis)

3
Last update : 29/09/2012
 
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1
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2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
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See also under
Dronedarone
2
Excipients-Vehicle-Preservatives (of drugs)
5
Thyroid hormones (exogenous)
1

Publications

In vivo probe-based confocal laser endomicroscopy in amiodarone-related pneumonia.
The European respiratory journal 2013 Dec;42;1646-58 2013 Dec
Severe amiodarone induced pulmonary toxicity.
Journal of thoracic disease 2012 Dec;4;667-70 2012 Dec
Lymphoid hyperplasia and eosinophilic pneumonia as histologic manifestations of amiodarone-induced lung toxicity.
The American journal of surgical pathology 2012 Apr;36;509-16 2012 Apr
Hypersensitivity pneumonitis associated with the use of temozolomide.
The European respiratory journal 2009 Apr;33;931-4 2009 Apr
Nodular amiodarone lung disease.
The American journal of surgical pathology 2008 Nov;32;1654-60 2008 Nov
Histiocytic lesions and proliferations in the lung.
Seminars in diagnostic pathology 2007 Aug;24;162-82 2007 Aug
An unintended consequence: fatal amiodarone pulmonary toxicity in an older woman.
Journal of the American Medical Directors Association 2006 Oct;7;510-3 2006 Oct
Fatal pulmonary toxicity occurring within two weeks of initiation of amiodarone.
The American journal of cardiology 2002 Apr 01;89;896-8 2002 Apr 01
Amiodarone pulmonary toxicity: cytopathology, ultrastructure, and immunocytochemistry.
Annals of diagnostic pathology 1997 Oct;1;47-56 1997 Oct
Amiodarone-induced pulmonary toxicity. Immunoallergologic tests and bronchoalveolar lavage phospholipid content.
Chest 1991 Feb;99;363-9 1991 Feb
CT-pathology correlation of amiodarone lung.
Journal of computer assisted tomography 1990;14;760-5 1990
Amiodarone pulmonary toxicity: clinical and subclinical features.
The Quarterly journal of medicine 1986 May;59;449-71 1986 May
Electron microscopic demonstration of lysosomal inclusion bodies in lung, liver, lymph nodes, and blood leukocytes of patients with amiodarone pulmonary toxicity.
The American journal of medicine 1985 Mar;78;506-12 1985 Mar
Lung disease caused by amiodarone, a new antiarrythmic agent.
Radiology 1983 May;147;339-44 1983 May
Amiodarone pulmonary toxicity.
Annals of internal medicine 1982 Dec;97;839-45 1982 Dec

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