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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amiodarone

5

XVIII.k Eye-catcher: An electron-dense liver on unenhanced CT

2
Last update : 31/08/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
More detailed checklist
See also under
Dronedarone
2
Excipients-Vehicle-Preservatives (of drugs)
5
Thyroid hormones (exogenous)
1

Publications

Organizing pneumonia secondary to amiodarone treatment.
Heliyon 2022 Sep;8;e10630 2022 Sep
Amiodarone-Induced Multi-Systemic Toxicity Involving the Liver, Lungs, Thyroid, and Eyes: A Case Report.
Frontiers in cardiovascular medicine 2022;9;839441 2022
Amiodarone-induced hepatic and pulmonary toxicity.
Postgraduate medical journal 2018 Oct;94;603 2018 Oct
Analysis of computed tomography density of liver before and after amiodarone administration.
Japanese journal of radiology 2018 May;36;340-344 2018 May
High liver density on CT imaging due to amiodarone toxicity.
Wiener klinische Wochenschrift 2018 Mar;130;220-221 2018 Mar
Hepatic computed tomography changes caused by amiodarone.
The Korean journal of internal medicine 2015 Sep;30;745-6 2015 Sep
Amiodarone toxicity showing high liver density on CT scan with normal liver function and plasma amiodarone levels in a long-term amiodarone user.
International journal of cardiology 2014 Mar 15;172;494-5 2014 Mar 15
An enlarged heart with hyperdense consolidation.
The Netherlands journal of medicine 2013;71;317, 321 2013
Increased hepatic density and phospholipidosis due to amiodarone.
AJR. American journal of roentgenology 1985 Mar;144;541-6 1985 Mar
Dense liver in a 72-year-old woman with congestive heart failure.
Investigative radiology 1985 Dec;20;911-5 1985 Dec

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