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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amiodarone

5

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

2
Last update : 06/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Dronedarone
2
Excipients-Vehicle-Preservatives (of drugs)
5
Thyroid hormones (exogenous)
1

Publications

Diffuse alveolar hemorrhage and acute eosinophilic pneumonia: A rare form of amiodarone pulmonary toxicity diagnosed by bronchoalveolar lavage.
Journal of cardiology cases 2023 Mar;27;93-96 2023 Mar
Case report of amiodarone-associated allergic pneumonitis amidst the COVID-19 pandemic.
Reviews in cardiovascular medicine 2021 Mar 30;22;181-184 2021 Mar 30
Eosinophilic pneumonia: A rare manifestation of amiodarone toxicity diagnosed using traditional bronchoscopy.
Respiratory medicine case reports 2019;27;100856 2019
Lymphoid hyperplasia and eosinophilic pneumonia as histologic manifestations of amiodarone-induced lung toxicity.
The American journal of surgical pathology 2012 Apr;36;509-16 2012 Apr

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