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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ocrelizumab

1

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

1
Last update : 23/11/2024
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Ocrelizumab-associated cryptogenic organizing pneumonia in multiple sclerosis: Two case reports and comprehensive literature review.
Multiple sclerosis (Houndmills, Basingstoke, England) 2024 Nov 21;;13524585241295677 2024 Nov 21
Organizing pneumonia following ocrelizumab use in a patient with multiple sclerosis: A case report.
Tuberkuloz ve toraks 2023 Mar;71;107-111 2023 Mar

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