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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Ocrelizumab
1
An anti-CD20
Last update :
29/07/2024
I - Interstitial/parenchymal lung disease
I.b
Pneumonitis (ILD)
1
I.d
Organizing pneumonia pattern (an area or areas of consolidation on imaging)
1
I.ao
Pulmonary infiltrates
1
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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