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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Minocycline

4

X.a DRES syndrome - DRESS-like reaction

1
Last update : 29/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Antibiotics
5
Doxycycline
1
Minocycline (topical, transdermal)
1
Tetracycline
1

Publications

Visceral involvements and long-term sequelae in drug-induced hypersensitivity syndrome.
The Medical clinics of North America 2010 Jul;94;743-59, xi 2010 Jul
Minocycline-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome with persistent myocarditis.
Journal of the American Academy of Dermatology 2010 Feb;62;315-8 2010 Feb
[Severe drug rash with eosinophilia and systemic symptoms after treatment with minocycline].
Revue des maladies respiratoires 2007 Sep;24;892-5 2007 Sep
Minocycline-induced central nervous system-pulmonary hypersensitivity syndrome.
International journal of dermatology 2003 Apr;42;316-7 2003 Apr
[Systemic reaction induced my minocycline treatment: a report of four patients and a review of the literature].
La Revue de medecine interne 1999 Oct;20;869-74 1999 Oct
Fever, lymphadenopathy, eosinophilia, lymphocytosis, hepatitis, and dermatitis: a severe adverse reaction to minocycline.
Journal of the American Academy of Dermatology 1997 Feb;36;347-50 1997 Feb
Serious adverse reactions induced by minocycline. Report of 13 patients and review of the literature.
Archives of dermatology 1996 Aug;132;934-9 1996 Aug

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