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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Naproxen

2

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 05/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Nonsteroidal anti-inflammatory drugs (NSAIDs)
5

Publications

Severe asthma after naproxen.
Lancet (London, England) 1987 May 30;1;1270 1987 May 30
Severe asthma induced by naproxen--a case report and review of the literature.
Annals of allergy 1980 Dec;45;372-5 1980 Dec
Asthmatic attacks induced in aspirin-sensitive patients by diclofenac and naproxen.
British medical journal 1977 Jul 23;2;231-2 1977 Jul 23

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