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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Anticoagulants, oral (vitamin K antagonists-VKA)

5

VIII.v Retropharyngeal hematoma (may cause UAO)

2
Last update : 01/10/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Acenocoumarol
1
Anticoagulants, direct oral (anti-thrombin, -IIa, -Xa) - NOAC
3
Brodifacoum
4
Coumadin
1
Dicoumarol
1
Heparin
4
Heparin, low-m.w.
1
Phenprocoumon
1
Superwarfarins (vitamin K super antagonist rodenticides)
4
Thrombolytic (fibrinolytic) agents
3
Warfarin
5

Publications

Images in Clinical Medicine. Spontaneous Retropharyngeal Hematoma.
The New England journal of medicine 2016 Jan 21;374;e3 2016 Jan 21
Anticoagulation and spontaneous retropharyngeal hematoma.
The Journal of emergency medicine 2003 May;24;389-94 2003 May
Retropharyngeal and bowel hematomas in an anticoagulated patient.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 1994;1;67-72 1994
Retropharyngeal hematoma. A complication of therapy with anticoagulants.
Archives of otolaryngology (Chicago, Ill. : 1960) 1975 Sep;101;565-8 1975 Sep

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