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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Tiopronine

1

X.j Myopathy-Myositis-Polymyositis (see also under Xba)

1
Last update : 14/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[Polymyositis induced by tiopronine].
Presse medicale (Paris, France : 1983) 1999 May 1-8;28;911-2 1999 May 1-8
[Tiopronin-induced polymyositis confirmed by histology].
Revue du rhumatisme (Ed. francaise : 1993) 1993 Jan;60;78-9 1993 Jan

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