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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Tosufloxacin

1

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
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Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Quinolones
3

Publications

Pulmonary infiltration with eosinophilia (PIE) syndrome induced by antibiotics, PIPC and TFLX during cancer treatment.
Oral oncology 2001 Jul;37;471-5 2001 Jul
[Drug-induced pneumonitis with eosinophilic infiltration due to tosufloxacin tosilate].
Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 1998 Jul;36;618-22 1998 Jul

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