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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Factor VIIa

1

VI.a Pulmonary embolism - Venous thrombosis/thromboembolism

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Pulmonary embolism after administration of recombinant activated Factor VII for major obstetric hemorrhage.
Journal of clinical anesthesia 2012 Sep;24;508-9 2012 Sep
Thromboembolic complications associated with factor VIIa administration.
The Journal of trauma 2007 Mar;62;564-9 2007 Mar
Pulmonary embolism after sequential use of recombinant factor VIIa and activated prothrombin complex concentrate in a factor VIII inhibitor patient.
Thrombosis and haemostasis 2002 May;87;925-6 2002 May

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