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Factor VIIa

Recombinant human activated factor VII (rh FVIIa). Thrombotic complications may not occur when FVIIa is given in the lung via lavage to control severe alveolar hemorrhage

Last update : 27/01/2014

VI.a Pulmonary embolism - Venous thrombosis/thromboembolism

VIII.s Endoluminal clotting

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

More detailed checklist

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

Factor VIIa

VI.a Pulmonary embolism - Venous thrombosis/thromboembolism

VIII.s Endoluminal clotting