Pneumotox » Drug » Quinine » I.c - Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Quinine

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Although no definite PIE case is available, quinine can prouce both the DRESS syndrome and/o peripheral eosinophilia. So, PIE is a possibility. We are monitoring the literature daily

Last update : 08/09/2019

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

More detailed checklist

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

Quinine

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

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