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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Celecoxib

2

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

1
Last update : 13/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
COX2 inhibitors
2
Nonsteroidal anti-inflammatory drugs (NSAIDs)
5

Publications

Anaphylactic drug reaction to celecoxib and sulfamethoxazole: cross reactivity or coincidence?
Allergy 2003 Oct;58;1072 2003 Oct
Selective celecoxib-associated anaphylactoid reaction.
The Journal of allergy and clinical immunology 2003 Jun;111;1404-5 2003 Jun
Identification of sulfonamide-like adverse drug reactions to celecoxib in the World Health Organization database.
Current medical research and opinion 2001;17;210-6 2001

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