A common side- or adverse effect from the drug affecting upp to 44% of the patients (PMID 19381453). Typically lymphocyte-rich. Sometimes chylous (PMID 19838099). Management guidelines at PMID 20375898
v2.2
The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment