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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Dasatinib

4

V.m Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)

2
Last update : 26/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Bosutinib
2
Imatinib
3
Ponatinib
2

Publications

Incidence, risk factors and management of pleural effusions during dasatinib treatment in unselected elderly patients with chronic myelogenous leukaemia.
Hematological oncology 2013 Jun;31;103-9 2013 Jun
Extensive pleural and pericardial effusion in chronic myeloid leukemia during treatment with dasatinib at 100 mg or 50 mg daily.
Haematologica 2011 Jan;96;163-6 2011 Jan

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