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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Paraldehyde

1

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Noncardiac pulmonary edema.
Chest 1983 Jun;83;934 1983 Jun
Noncardiac pulmonary edema following administration of parenteral paraldehyde.
Chest 1982 Sep;82;371-2 1982 Sep
Cyanosis, cough, and hypotension following intravenous administration of paraldehyde.
Pediatrics 1976 Jan;57;158-9 1976 Jan

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