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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
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Anaphylaxis-Anaphylactoid reaction (can be fatal)
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Last update :
30/04/2012
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Black stone (para-phenylenediamine)
Fluorescein
Indigo
Indigo-indirubin
Methylene blue
Patent blue
Sudan red dye
Publications
Images in clinical medicine. Anaphylaxis associated with blue dye.
Anaphylaxis to patent blue V: a case series and proposed diagnostic protocol.
Biphasic anaphylactic reaction to blue dye during sentinel lymph node biopsy.
Near-fatal anaphylaxis to patent blue V.
Toxicity of Food Drug and Cosmetic Blue No. 1 dye in critically ill patients.
Anaphylactic reaction to methylene blue dye after laparoscopic chromopertubation.
Anaphylactic/anaphylactoid reaction to contrast dye administered in the ureter.
Hazards of intravenous indigo carmine, fluorescein, and methylene blue.