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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Kayexalate

2

XV.aq Path: Resin (Kayexalate-Sevelamer) lung

1
Last update : 20/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[Granulomatous lung disease induced by kayexalate inhalation during immunotherapy for metastatic melanoma].
Revue des maladies respiratoires 2021 Jun;38;664-668 2021 Jun
Refractory hypoxemia due to sodium polystyrene sulfonate (kayexalate) aspiration.
Annals of the American Thoracic Society 2014 Jul;11;993-5 2014 Jul
Sodium polystyrene sulfonate (Kayexalate) aspiration.
Diagnostic pathology 2008 Jun 17;3;27 2008 Jun 17
Association of serum lipid levels with HIV serostatus, specific antiretroviral agents, and treatment regimens.
Journal of acquired immune deficiency syndromes (1999) 2007 May 01;45;34-42 2007 May 01
Kayexalate (sodium polystyrene sulfonate) aspiration.
Archives of pathology & laboratory medicine 2005 Jan;129;125 2005 Jan
Sodium polystyrene sulfonate (kayexalate) aspiration: histologic appearance and infrared microspectrophotometric analysis of two cases.
Archives of pathology & laboratory medicine 1996 Oct;120;967-9 1996 Oct

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