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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Isoxsuprine

2

II.a Pulmonary edema, noncardiogenic (NCPE)

2
Last update : 24/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Isoxsuprine and pulmonary edema.
Chest 1985 Oct;88;643-4 1985 Oct
Pulmonary edema associated with isoxsuprine therapy.
American journal of obstetrics and gynecology 1984 Mar 01;148;625-9 1984 Mar 01
Pulmonary edema occurring after isoxsuprine and dexamethasone treatment for preterm labor: Case report.
Journal of perinatal medicine 1983;11;272-7 1983
Pulmonary complications of isoxsuprine therapy in the gravida.
Obstetrics and gynecology 1982 Jun;59;38S-42S 1982 Jun

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