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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Vertebroplasty (kyphoplasty)
4
VI.h
Cement embolism
2
Last update :
10/12/2013
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Cement (bone cement, kyphoplasty, vertebroplasty)
Methacrylate - Methylmethacrylate
Publications
Pulmonary cement embolization after vertebroplasty requiring pulmonary wedge resection.
Polymethylmethacrylate cement pulmonary embolism and infarct.
