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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Aniline - Aminophenols

1

XIV.a Methemoglobinemia

1
Last update : 04/09/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
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Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Aniline, p-chloro-
1
Chemicals
5

Publications

Severe methemoglobinemia and hemolytic anemia from aniline purchased as 2C-E (4-ethyl-2,5-dimethoxyphenethylamine), a recreational drug, on the Internet - Oregon, 2011.
MMWR. Morbidity and mortality weekly report 2012 Feb 10;61;85-8 2012 Feb 10
Toxicology laboratory analysis and human exposure to p-chloroaniline.
Clinical toxicology (Philadelphia, Pa.) 2009 Feb;47;132-6 2009 Feb

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