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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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VIII.as

Acute laryngeal dystonia

Last update : 01/01/1970
 

Causative drugs

1

Neuroleptics - Antipsychotics

II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
VI.a VI - Pulmonary vasculopathies
VI.a - Pulmonary embolism - Venous thrombosis/thromboembolism
VIII.e VIII - Central-large-upper airway (incl. pharyngeal-nasal) involvement
VIII.e - Laryngospasm (a.k.a. laryngismus)
VIII.h VIII - Central-large-upper airway (incl. pharyngeal-nasal) involvement
VIII.h - Vocal cord dysfunction, adduction, closure, injury
VIII.as VIII - Central-large-upper airway (incl. pharyngeal-nasal) involvement
VIII.as - Acute laryngeal dystonia
IX.b IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
IX.b - Respiratory dyskinesia
IX.c IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
IX.c - Chest wall muscle rigidity - Stiff/wooden chest
IX.k IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
IX.k - Trismus (lockjaw)
XI.g XI - Miscellaneous
XI.g - Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)
XI.j XI - Miscellaneous
XI.j - Esophageal dysmotility
XI.o XI - Miscellaneous
XI.o - Dysphagia
XV.c XV - Pathology
XV.c - Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)
XV.f XV - Pathology
XV.f - Path: Diffuse alveolar damage (DAD-pattern) (see also IL)
XVII.a XVII - Infections & related conditions
XVII.a - Respiratory tract infection incl. pneumonia
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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