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Drug overdose

See also under drugs on right panel. Pulmonary edema (PE) was common in heroin addicts ('overdose'). PE is also very common in executed inmates in whom high doses of drugs are given.

Last update : 26/09/2020

II.a Pulmonary edema, noncardiogenic (NCPE)

IX.d Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

XI.r Death following exposure or poisoning

XII.e Takotsubo (stress) cardiomyopathy

XXIII.a Acute respiratory distress

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

More detailed checklist

The Drug-Induced Respiratory Disease Website