Pneumotox » Drug » Salbutamol

Salbutamol - Albuterol

Most adverse events follow i.v. administration of ß2 agonists in parturient women and are in the form of acute pulmonary edema. Transient vehicle-induced bronchospasm may follow salbutamol inhalation

Last update : 10/10/2018

II.a Pulmonary edema, noncardiogenic (NCPE)

II.d Pulmonary edema, cardiogenic

IV.a Bronchospasm - Wheezing - Asthma

XI.d Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea

XII.e Takotsubo (stress) cardiomyopathy

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

More detailed checklist

The Drug-Induced Respiratory Disease Website