See under each specific drug, as each TKI has its own particulars. Reviews at PMID 18252919, 18551203, 22252615, 23152005, 23152006. The maked disparity in incidence between Japan and Asia vs. the rest of the world is unexplained (heterogenous DI-ILD definition, reporting bias and ethnicity are among the possibilities)

Last update : 07/05/2019
I - Interstitial/parenchymal lung disease
II - Pulmonary edema - Acute lung injury - ARDS
III - Pulmonary/alveolar hemorrhage
V - Pleural and/or pericardial involvement
XII - Cardiovascular involvement / toxicity