Pneumotox » Drug » Vaccines

Vaccines

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A broad term. Please refer to specific vaccines in the list incl. anti-cancer vaccines

Last update : 26/02/2019

I.b Pneumonitis (ILD)

1

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

1

I.y Progression, acceleration or exacerbation of preexisting ILD/fibrosis

1

II.b ARDS - Acute lung injury

1

IV.a Bronchospasm - Wheezing - Asthma

1

VIII.a Angioedema (may cause UAO, asphyxia and death)

2

X.b Antiphospholipid antibodies w/wo the APL syndrome

1

X.d Lupus - Lupus syndrome (see also Vd)

2

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

2

X.m Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

1

X.s Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

1

Diagnosing DIRD

1

Drug and radiation history

2

Drug singularity - Correct identification of the drug

3

Consistent timing of exposure v. onset of symptoms

4

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

5

Careful exlusion of another cause

6

Remission of symptoms with removal of drug

7

Recurrence with rechallenge (rarely advisable)

8

Causality assessment

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