Pneumotox » Drug » Gabapentin

Gabapentin

2

Last update : 24/02/2018

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1

V.b Eosinophilic pleural effusion

1

VII.a Lymphadenopathy (intrathoracic)

1

VIII.a Angioedema (may cause UAO, asphyxia and death)

1

VIII.q Tongue involvement (edema, glossitis, hematoma)

1

IX.d Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

2

IX.p Disordered breathing during sleep - Sleep apnea

1

XI.r Death following exposure or poisoning

1

Diagnosing DIRD

1

Drug and radiation history

2

Drug singularity - Correct identification of the drug

3

Consistent timing of exposure v. onset of symptoms

4

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

5

Careful exlusion of another cause

6

Remission of symptoms with removal of drug

7

Recurrence with rechallenge (rarely advisable)

8

Causality assessment

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