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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Immunoglobulins, intravenous (IVIG)

3

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 09/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Hemotherapy (transfusion/infusion of whole blood, red cells, platelets, or blood products)
5

Publications

Transfusion-Related Acute Lung Injury After Immunoglobulin Infusion for Kawasaki Disease: A Case Report and Literature Review.
Global pediatric health 2017;4;2333794X17746545 2017
Multiorgan Failure From Cryoglobulinemic Vasculitis Following Intravenous Immunoglobulin Replacement Therapy.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2016 Dec;22;441-443 2016 Dec
Transfusion-related acute lung injury after transfusion of pooled immune globulin: a case report.
Transfusion 2014 Dec;54;3088-91 2014 Dec
Acute pulmonary edema as a complication of anti-snake venom therapy.
Indian journal of pediatrics 2001 Jan;68;81-2 2001 Jan
Transfusion-related acute lung injury after the infusion of IVIG.
Transfusion 2001 Feb;41;264-8 2001 Feb
Noncardiogenic pulmonary edema triggered by intravenous immunoglobulin in cancer-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome.
Nephron 1997;77;368-70 1997

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