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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Sulfasalazine

3

XII.d Myocarditis (can be fulminant)

1
Last update : 03/09/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Sulfamides - Sulfonamides
3

Publications

Fatal sulfasalazine-induced eosinophilic myocarditis in a patient with periodic fever syndrome.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2015;24;195-7 2015
The 3-week sulphasalazine syndrome strikes again.
Forensic science international 2001 Nov 01;122;79-84 2001 Nov 01

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