Pneumotox » Drug » Sulfamides - Sulfonamides

Sulfamides - Sulfonamides

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See under specific drugs

Last update : 30/10/2018

I.b Pneumonitis (ILD)

1

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

2

II.a Pulmonary edema, noncardiogenic (NCPE)

1

V.a Pleural effusion

1

VI.d Pulmonary vasculitis or capillaritis

1

X.a DRES syndrome - DRESS-like reaction

1

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

5

XII.d Myocarditis (can be fulminant)

1

XIV.a Methemoglobinemia

1

XIV.b Sulfhemoglobinemia

1

XV.g Path: Alveolar hemorrhage (see also IIIa)

-

XV.ac Path: Pulmonary vasculitis other than capillaritis

-

XXIV.a Veterinary: Pneumonitis - Interstitial lung disease

1

Diagnosing DIRD

1

Drug and radiation history

2

Drug singularity - Correct identification of the drug

3

Consistent timing of exposure v. onset of symptoms

4

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

5

Careful exlusion of another cause

6

Remission of symptoms with removal of drug

7

Recurrence with rechallenge (rarely advisable)

8

Causality assessment

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