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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Beta-2 agonists, B2 mimetics (parenteral)
3
XI.d
Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea
1
Last update :
19/03/2015
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
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Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Magnesium sulfate
Ritodrine
Salbutamol - Albuterol
Terbutaline (parenteral)
Tocolytic therapy
Publications
A paradoxical effect of bronchodilators.