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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cocaine

5

X.x ANCA positivity. Subclinical or with clinical manifestations

2
Last update : 27/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Crack cocaine
5
Levamisole
4
Levamisole-adulterated/tainted cocaine
5
Talc (inhaled, sniffed, i.v., intrapleural)
3

Publications

Demographic, Clinical, and Immunologic Correlates among a Cohort of 50 Cocaine Users Demonstrating Antineutrophil Cytoplasmic Antibodies.
The Journal of rheumatology 2019 Sep;46;1151-1156 2019 Sep
Antineutrophil cytoplasmic antibodies reacting with human neutrophil elastase as a diagnostic marker for cocaine-induced midline destructive lesions but not autoimmune vasculitis.
Arthritis and rheumatism 2004 Sep;50;2954-65 2004 Sep

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