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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Status post-hematopoietic stem cell (HSCT) or bone marrow transplantation (BMT)
5
II.a
Pulmonary edema, noncardiogenic (NCPE)
2
Last update :
28/08/2012
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
Publications
[Non-infectious pulmonary complications after the hematopoietic stem cell transplantation].
Non-infectious pulmonary complications after bone marrow transplantation.
Chest radiographic features of engraftment syndrome.
Engraftment syndrome and survival after respiratory failure post-bone marrow transplantation.