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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Corticosteroids, systemic (oral, parenteral)
5
XVII.o
Nocardia pulmonary/systemic infection
2
Last update :
10/02/2015
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Adrenocorticotropic hormone (ACTH)
Budesonide (p.o.)
Corticosteroids, inhaled (ICS)
Methylprednisolone
Prednisone
Salt (NaCl)
Publications
Clinical findings of 40 patients with nocardiosis: A retrospective analysis in a tertiary hospital.
Pulmonary infection with Nocardia species: a report of 10 cases and review.