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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Antibiotics
5
I.b
Pneumonitis (ILD)
1
Last update :
18/09/2018
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Amikacin
Aminoglycoside antibiotics
Amoxicillin
Bacitracin
Beta-lactam antibiotics
Cefazolin
Cefodroxil monohydrate
Cefotetan
Cefotiam
Cefpodoxime
Cefradoxil
Ceftaroline
Ceftriaxone
Cephalexin
Cephalosporin(s)
Ciprofloxacin
Colistin, inhaled
Colistin-Colimycin
Dactinomycin
Daptomycin
Doxycycline
Imipenem-cilastatin
Levofloxacin
Meropenem
Minocycline
Moxalactam
Moxifloxacin
Nitrofurantoin
Piperacilline
Polymyxin
Probiotics
Streptomycin
Tazobactam
Teicoplanin
Telithromycin
Tetracycline
Tosufloxacin
Publications
A case of drug induced lung injury caused by levofloxacin eye drops.