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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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E-cigarette - E-vaporizers - ENDS - Vaping - Dabbing

5

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

5

PMID 34484520

Last update : 19/09/2021
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Cannabinoids - Cannabinoid receptor agonists (synthetic)
5
Diacetyl (2,3-butanedione) flavoring agent
3
E-cigarette's, e-vaporizer's secondhand vapor (Passive vaping)
1
Flavoring agents
5
Glue sniffing
3
Inhalants (volatile substances)
5
Marijuana, cannabis (haschish, hash, bang, dab)
5
Nicotine
1
Nitrous oxide (N2O)
1
Sildenafil
1
Tadalafil
1
Tetrahydrocannabinol (THC)
5
Tobacco smoke - Cigarette smoking
5
Vitamin E acetate (vaped, inhaled)
5

Publications

Vaping-induced lung injury in a 21-year-old woman.
BMJ case reports 2020 Nov 30;13; 2020 Nov 30
Syndromic Surveillance for E-Cigarette, or Vaping, Product Use-Associated Lung Injury.
The New England journal of medicine 2020 Feb 20;382;766-772 2020 Feb 20
Severe Lung Injury Associated With Use of e-Cigarette, or Vaping, Products-California, 2019.
JAMA internal medicine 2020 06 01;180;861-869 2020 06 01
Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin - Final Report.
The New England journal of medicine 2020 03 05;382;903-916 2020 03 05
Acute Respiratory Failure Associated With Vaping.
Chest 2020 03;157;e63-e68 2020 03
Vaping-associated Acute Lung Injury: A Case Series.
American journal of respiratory and critical care medicine 2019 12 01;200;1430-1431 2019 12 01
Hypersensitivity Pneumonitis and Acute Respiratory Distress Syndrome From E-Cigarette Use.
Pediatrics 2018 06;141; 2018 06

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