PMID 31990264. Reached epidemic proportions mid-2019, then declining over the following months. THC, and vitamin-E acetate at the forefront of possible culprit agents. Substances of toxicological interest include ethylene glycol, glycerine, flavoring agents including diacetyl, cannabis (PMID 26347431), tetrahydrocannabinol THC (PMID 25383564, 31491070), vitamin E acetate, ‘sexual enhancers’ such as tadalafil, poppers (NO), or other drugs of abuse (PMID 30245461, 30835796). There is also the risk of nicotine poisoning if contents of a cartridge is taken orally and swallowed, notably by/in children. Careful differential diagnosis and history taking of exposure to tobacco smoke, inhalants, inhaled stimulants, inhaled drugs and/or substances of abuse is indicated in every patient. E-cigarette in patients on oxygen therapy may produce severe facial burns. Battery explosion and fire can injure the mouth, teeth, face, eye, skin and/or thigh.

Last update : 30/01/2020
I - Interstitial/parenchymal lung disease
II - Pulmonary edema - Acute lung injury - ARDS
III - Pulmonary/alveolar hemorrhage
IV - Airway involvement
V - Pleural and/or pericardial involvement
VII - Mediastinal involvement
VIII - Central-large-upper airway (incl pharyngeal-nasal) involvement
IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
X - Systemic/Distant conditions, syndromes and reactions
XI - Miscellaneous
XII - Cardiovascular involvement / toxicity
XIV - Hemoglobinopathies - Abnormal hemoglobin states (acquired)
XV - Pathology
XVI - Imaging
XVII - Infections & related conditions
XIX - Cytological, biochemical features of/in BAL, pleural fluid or FNA