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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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E-cigarette - E-vaporizers - ENDS - Vaping - Dabbing

5

XV.f Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

1
Last update : 08/09/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Cannabinoids - Cannabinoid receptor agonists (synthetic) (K2, Spice)
5
Diacetyl (2,3-butanedione) flavoring agent
3
E-cigarette's, e-vaporizer's secondhand vapor (Passive vaping)
1
Flavoring agents
5
Glue sniffing
3
Inhalants (volatile substances)
5
Marijuana, cannabis (haschish, hash, bang, dab)
5
Nicotine
1
Nitrous oxide (N2O)
1
Sildenafil
1
Tadalafil
1
Tetrahydrocannabinol (THC)
5
Tobacco smoke - Cigarette smoking
5
Vitamin E acetate (vaped, inhaled)
5

Publications

Acute Respiratory Failure Associated With Vaping.
Chest 2020 Mar;157;e63-e68 2020 Mar
Fatal e-cigarette or vaping associated lung injury (EVALI): a first case report in Europe.
The European respiratory journal 2020 Jul;56; 2020 Jul
Lung Biopsy Findings in Severe Pulmonary Illness Associated With E-Cigarette Use (Vaping).
American journal of clinical pathology 2020 Jan 01;153;30-39 2020 Jan 01
Vaping-related Lung Injury in an Adolescent.
American journal of respiratory and critical care medicine 2020 Feb 15;201;481-482 2020 Feb 15
Pathology of Vaping-Associated Lung Injury.
The New England journal of medicine 2019 Oct 31;381;1780-1781 2019 Oct 31

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