Pneumotox » Drug » Anorexigens - Anorectic agents - Appetite suppressants

Anorexigens - Anorectic agents - Appetite suppressants

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Anorectic agents, appetite suppressants. Amphetamide-derived medications can effectuate pulmonary hypertension. See in particular under aminorex, benfluorex, fenfluramine, dexfenfluramine, nordexfenfluramine. See also under valvular heart disease XIIb

Last update : 22/05/2015

VI.b Pulmonary arterial hypertension

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XI.r Death following exposure or poisoning

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XII.b Valvular heart disease and/or dysfunction

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Diagnosing DIRD

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Drug and radiation history

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Drug singularity - Correct identification of the drug

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Consistent timing of exposure v. onset of symptoms

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Clinical, imaging, BAL, pathological pattern consistent with the specific drug

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Careful exlusion of another cause

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Remission of symptoms with removal of drug

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Recurrence with rechallenge (rarely advisable)

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Causality assessment

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