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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Angiotensin II receptor blockers (ARB) - Sartans

3

IV.d Cough (lone)

2
Last update : 10/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Angiotensin converting enzyme inhibitors (ACEI)
5
Candesartan
1
Eprosartan
1
Irbesartan
3
Losartan
2
Olmesartan
1
Telmisartan
2
Valsartan
1

Publications

Incidence of adverse events with telmisartan compared with ACE inhibitors: evidence from a pooled analysis of clinical trials.
Patient preference and adherence 2012;6;1-9 2012
Cough induced by losartan with resolution after substitution with enalapril.
Clinical therapeutics 2008 Mar;30;548-51 2008 Mar

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