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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Opiates - Opioids - Opium
5
II.a
Pulmonary edema, noncardiogenic (NCPE)
2
Last update :
02/09/2012
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Antidotes
Body packing
Cannabinoids - Cannabinoid receptor agonists (synthetic) (K2, Spice)
Cannabis oil, paste, resin-H oil-Cannabidiol (inhaled)
Diacetylmorphine
Ethanol (ethyl alcohol, 'alcohol')
Fentanyl
Heroin (inhaled, insufflated, snorted)
Heroin (intravenous)
MT-45
Morphine
Naloxone
Opioids (synthetic)
Opium
Sufentanil
U-47700
Publications
Fatal intoxication with new synthetic cannabinoids AMB-FUBINACA and EMB-FUBINACA.
Clinical images in medical toxicology: heroin overdose with non-cardiogenic pulmonary edema.
Thoracic complications of illicit drug use: an organ system approach.
Non-cardiogenic pulmonary edema after narcotic treatment for cancer pain.
Acute pulmonary edema following naloxone reversal of high-dose morphine anesthesia.