I.t

Pneumoconiosis (silicosis, talcosis...)

(Fr: pneumoconiose-talcose). Mineral dust-induced lung disease. Mainly due to exposure to drugs (mostly abused) containing silica or talc. Not unlike occupational silicosis, large airway involvement remains a possibility (PMID 18583512)

Last update : 01/01/1970
 

Causative drugs

8

Abused drugs/substances (illicit-, street drugs - IV/inhaled)

I.e I - Interstitial/parenchymal lung disease
I.e - Acute eosinophilic pneumonia (AEP)
I.j I - Interstitial/parenchymal lung disease
I.j - Lipoid pneumonia, exogenous
I.m I - Interstitial/parenchymal lung disease
I.m - ILD with a granulomatous component
I.s I - Interstitial/parenchymal lung disease
I.s - A mass or masses
I.t I - Interstitial/parenchymal lung disease
I.t - Pneumoconiosis (silicosis, talcosis...)
II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
III.a III - Pulmonary/alveolar hemorrhage
III.a - Alveolar hemorrhage, diffuse (DAH)
IV.a IV - Airway involvement
IV.a - Bronchospasm - Wheezing - Asthma
IV.f IV - Airway involvement
IV.f - Severe, catastrophic asthma attack (can be fatal)
IV.g IV - Airway involvement
IV.g - Syncope - Cough syncope
V.f V - Pleural and/or pericardial involvement
V.f - Pneumothorax
V.q V - Pleural and/or pericardial involvement
V.q - Empyema
V.ab V - Pleural and/or pericardial involvement
V.ab - Pneumothorax, bilateral
VI.b VI - Pulmonary vasculopathies
VI.b - Pulmonary arterial hypertension
VI.c VI - Pulmonary vasculopathies
VI.c - Pulmonary veno-occlusive disease
VI.g VI - Pulmonary vasculopathies
VI.g - Foreign body vasculopathy (Excipient lung disease)
VI.i VI - Pulmonary vasculopathies
VI.i - Acute pulmonary hypertension
VI.j VI - Pulmonary vasculopathies
VI.j - Mercury pulmonary embolism
VI.r VI - Pulmonary vasculopathies
VI.r - Septic pulmonary embolism
VI.t VI - Pulmonary vasculopathies
VI.t - Pulmonary artery aneurysm(s)
VII.h VII - Mediastinal involvement
VII.h - Pneumomediastinum (may cause UAO)
VII.i VII - Mediastinal involvement
VII.i - Mediastinitis
VIII.c VIII - Central-large-upper airway (incl pharyngeal-nasal) involvement
VIII.c - Upper airway obstruction other than angioedema or hematoma
VIII.d VIII - Central-large-upper airway (incl pharyngeal-nasal) involvement
VIII.d - Thermal (burns, frostbite), chemical or caustic facial and/or airway injury
VIII.ai VIII - Central-large-upper airway (incl pharyngeal-nasal) involvement
VIII.ai - Nasal, palatal and/or pharyngeal pathology
IX.a IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
IX.a - Diaphragm/inspiratory muscle weakness/paralysis (w/wo ARF)
IX.s IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
IX.s - Botulism - Wound botulism
X.m X - Systemic/Distant conditions, syndromes and reactions
X.m - Vascultis (Pulmonary and/or systemic) - ANCA status unknown or negative)
X.u X - Systemic/Distant conditions, syndromes and reactions
X.u - Multiple organ dysfunction/failure (MODS/MOF)
X.ac X - Systemic/Distant conditions, syndromes and reactions
X.ac - Anti-GBM antibody disease (Goodpasture-like or flare of preexisting GS)
X.bb X - Systemic/Distant conditions, syndromes and reactions
X.bb - Talc retinopathy
XI.b XI - Miscellaneous
XI.b - Chest pain (acute or subacute), lone or prominent
XI.g XI - Miscellaneous
XI.g - Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)
XI.m XI - Miscellaneous
XI.m - Pulmonary emphysema - Lung cysts or bullae
XI.r XI - Miscellaneous
XI.r - Death following exposure or poisoning
XII.g XII - Cardiovascular involvement / toxicity
XII.g - Myocardial ischemia/infarction - Coronary artery disease, acute
XII.i XII - Cardiovascular involvement / toxicity
XII.i - Endocarditis (infective)
XII.v XII - Cardiovascular involvement / toxicity
XII.v - Hypertrophic cardiomyopathy
XV.q XV - Pathology
XV.q - Path: Foreign body deposits/granulomatous reaction
XV.s XV - Pathology
XV.s - Path: Pneumoconiosis (silicosis, talcosis, talcoma)
XV.v XV - Pathology
XV.v - Path: Micronodular organizing pneumonia/BOOP
XV.ag XV - Pathology
XV.ag - Path: Foreign body embolism, microangiopathy, vasculopathy
XV.al XV - Pathology
XV.al - Path: Pulmonary hypertension incl. angiomatoid vasculopathy
XVI.u XVI - Imaging
XVI.u - Imaging: A miliary pattern (diffuse random micronodules)
XVI.v XVI - Imaging
XVI.v - Imaging: Centrilobular micronodules (can be diffuse)
XVI.ab XVI - Imaging
XVI.ab - Imaging: Cavitating lung nodule, mass or nodules (see also Iq, XIs, XIIi, XVIaa and XVIIp)
XVI.ae XVI - Imaging
XVI.ae - Imaging: A pattern similar to pneumoconiotic progressive massive fibrosis (PMF)
XVI.af XVI - Imaging
XVI.af - Imaging: Lung cysts or bullae (see also XVI ah/bf)
XVII.a XVII - Infections & related conditions
XVII.a - Respiratory tract infection incl. pneumonia
XVII.b XVII - Infections & related conditions
XVII.b - Opportunistic pulmonary/systemic infection
XVII.g XVII - Infections & related conditions
XVII.g - Tuberculosis (pulmonary, extrapulmonary, reactivation or de novo)
XVII.p XVII - Infections & related conditions
XVII.p - Lung abscess/abscesses (see also VIr)
XVII.s XVII - Infections & related conditions
XVII.s - Sternoclavicular septic arthritis
XVII.u XVII - Infections & related conditions
XVII.u - Epidural abscess
XVII.al XVII - Infections & related conditions
XVII.al - Osteomyelitis (notably of thoracic bones)
XVIII.t XVIII - Distinctive patterns - 'Eye-catchers'
XVIII.t - Eye catcher: Purpuric/Ecchymotic/Cyanotic lesions of the earlobes and/or nose
XVIII.u XVIII - Distinctive patterns - 'Eye-catchers'
XVIII.u - Eye catcher: Talc retinopathy
3

Excipients - Vehicle - Preservatives

I.c I - Interstitial/parenchymal lung disease
I.c - Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
I.d I - Interstitial/parenchymal lung disease
I.d - Organizing pneumonia pattern (an area or areas of consolidation on imaging)
I.e I - Interstitial/parenchymal lung disease
I.e - Acute eosinophilic pneumonia (AEP)
I.g I - Interstitial/parenchymal lung disease
I.g - Pulmonary fibrosis (Not otherwise specified)
I.m I - Interstitial/parenchymal lung disease
I.m - ILD with a granulomatous component
I.t I - Interstitial/parenchymal lung disease
I.t - Pneumoconiosis (silicosis, talcosis...)
II.a II - Pulmonary edema - Acute lung injury - ARDS
II.a - Pulmonary edema, noncardiogenic (NCPE)
IV.a IV - Airway involvement
IV.a - Bronchospasm - Wheezing - Asthma
IV.f IV - Airway involvement
IV.f - Severe, catastrophic asthma attack (can be fatal)
IV.i IV - Airway involvement
IV.i - Foreign body aspiration bronchiolitis
VI.b VI - Pulmonary vasculopathies
VI.b - Pulmonary arterial hypertension
VI.e VI - Pulmonary vasculopathies
VI.e - Fat/oil embolism - The FES embolism syndrome
VI.g VI - Pulmonary vasculopathies
VI.g - Foreign body vasculopathy (Excipient lung disease)
X.f X - Systemic/Distant conditions, syndromes and reactions
X.f - Anaphylaxis
X.g X - Systemic/Distant conditions, syndromes and reactions
X.g - Hypersensitivity reactions (may involve skin, throat and/or airways)
X.u X - Systemic/Distant conditions, syndromes and reactions
X.u - Multiple organ dysfunction/failure (MODS/MOF)
XI.d XI - Miscellaneous
XI.d - Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea
XII.n XII - Cardiovascular involvement / toxicity
XII.n - Cardiovascular collapse - Cardiogenic shock
XV.q XV - Pathology
XV.q - Path: Foreign body deposits/granulomatous reaction
XV.ae XV - Pathology
XV.ae - Path: Lipid/fat embolism (see also VIe)
XVI.q XVI - Imaging
XVI.q - Imaging: A pattern similar/consistent to/with IPF
XVI.v XVI - Imaging
XVI.v - Imaging: Centrilobular micronodules (can be diffuse)
2

Marijuana, cannabis (haschish, hash, bang, dab)

I.a I - Interstitial/parenchymal lung disease
I.a - Pneumonitis (ILD), acute, severe (may occasion an ARDS picture)
I.c I - Interstitial/parenchymal lung disease
I.c - Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
I.e I - Interstitial/parenchymal lung disease
I.e - Acute eosinophilic pneumonia (AEP)
I.j I - Interstitial/parenchymal lung disease
I.j - Lipoid pneumonia, exogenous
I.n I - Interstitial/parenchymal lung disease
I.n - Pulmonary alveolar proteinosis (PAP)
I.t I - Interstitial/parenchymal lung disease
I.t - Pneumoconiosis (silicosis, talcosis...)
I.an I - Interstitial/parenchymal lung disease
I.an - Hypersensitivity pneumonitis pattern
I.ao I - Interstitial/parenchymal lung disease
I.ao - Pulmonary infiltrates, not specified otherwise
II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
III.a III - Pulmonary/alveolar hemorrhage
III.a - Alveolar hemorrhage, diffuse (DAH)
III.c III - Pulmonary/alveolar hemorrhage
III.c - Hemoptysis
IV.d IV - Airway involvement
IV.d - Cough (lone)
V.f V - Pleural and/or pericardial involvement
V.f - Pneumothorax
V.ab V - Pleural and/or pericardial involvement
V.ab - Pneumothorax, bilateral
VII.h VII - Mediastinal involvement
VII.h - Pneumomediastinum (may cause UAO)
VIII.w VIII - Central-large-upper airway (incl pharyngeal-nasal) involvement
VIII.w - Uvulitis, uvular edema
X.f X - Systemic/Distant conditions, syndromes and reactions
X.f - Anaphylaxis
X.ac X - Systemic/Distant conditions, syndromes and reactions
X.ac - Anti-GBM antibody disease (Goodpasture-like or flare of preexisting GS)
XI.b XI - Miscellaneous
XI.b - Chest pain (acute or subacute), lone or prominent
XI.m XI - Miscellaneous
XI.m - Pulmonary emphysema - Lung cysts or bullae
XI.s XI - Miscellaneous
XI.s - Sniffing death - Death from inhalation of compound
XI.av XI - Miscellaneous
XI.av - Deterioration of graft function in SOT recipients
XII.c XII - Cardiovascular involvement / toxicity
XII.c - Pericardial effusion (w/wo tamponade)
XII.d XII - Cardiovascular involvement / toxicity
XII.d - Myocarditis
XII.g XII - Cardiovascular involvement / toxicity
XII.g - Myocardial ischemia/infarction - Coronary artery disease, acute
XII.l XII - Cardiovascular involvement / toxicity
XII.l - Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
XII.s XII - Cardiovascular involvement / toxicity
XII.s - Conduction disorders - Heart block (bundle branch- or AV-)
XII.w XII - Cardiovascular involvement / toxicity
XII.w - Asystole
XII.af XII - Cardiovascular involvement / toxicity
XII.af - Coronary arterial spasm
XIII.a XIII - Neoplastic conditions
XIII.a - Lung cancer
XV.k XV - Pathology
XV.k - Path: Desquamative interstitial pneumonia (DIP-pattern)
XV.n XV - Pathology
XV.n - Path: Pulmonary alveolar proteinosis pattern (PAP pattern)
XV.p XV - Pathology
XV.p - Path: Exogenous lipoid pneumonia
XV.q XV - Pathology
XV.q - Path: Foreign body deposits/granulomatous reaction
XV.s XV - Pathology
XV.s - Path: Pneumoconiosis (silicosis, talcosis, talcoma)
XV.v XV - Pathology
XV.v - Path: Micronodular organizing pneumonia/BOOP
XVII.a XVII - Infections & related conditions
XVII.a - Respiratory tract infection incl. pneumonia
XVII.c XVII - Infections & related conditions
XVII.c - Aspergillosis, pulmonary (invasive, allergic [ABPA], or mycetoma)
XVII.g XVII - Infections & related conditions
XVII.g - Tuberculosis (pulmonary, extrapulmonary, reactivation or de novo)
1

Methadone

I.t I - Interstitial/parenchymal lung disease
I.t - Pneumoconiosis (silicosis, talcosis...)
II.a II - Pulmonary edema - Acute lung injury - ARDS
II.a - Pulmonary edema, noncardiogenic (NCPE)
II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
II.f II - Pulmonary edema - Acute lung injury - ARDS
II.f - Hypoxemia, low saturation (may occur in isolation)
VI.b VI - Pulmonary vasculopathies
VI.b - Pulmonary arterial hypertension
VI.g VI - Pulmonary vasculopathies
VI.g - Foreign body vasculopathy (Excipient lung disease)
IX.c IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
IX.c - Chest wall muscle rigidity - Stiff chest - Tetany
IX.d IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
IX.d - Respiratory depression-Hypoventilation (See also under XIe)
IX.e IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
IX.e - Disordered breathing pattern - Cheynes-Stokes respiration
IX.i IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
IX.i - Respiratory arrest - Apnea
XI.r XI - Miscellaneous
XI.r - Death following exposure or poisoning
XII.e XII - Cardiovascular involvement / toxicity
XII.e - Takotsubo (stress) cardiomyopathy
XII.l XII - Cardiovascular involvement / toxicity
XII.l - Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
XII.p XII - Cardiovascular involvement / toxicity
XII.p - QT prolongation
XII.t XII - Cardiovascular involvement / toxicity
XII.t - Torsades de pointe
1

Methamphetamine

I.a I - Interstitial/parenchymal lung disease
I.a - Pneumonitis (ILD), acute, severe (may occasion an ARDS picture)
I.t I - Interstitial/parenchymal lung disease
I.t - Pneumoconiosis (silicosis, talcosis...)
II.a II - Pulmonary edema - Acute lung injury - ARDS
II.a - Pulmonary edema, noncardiogenic (NCPE)
II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
III.a III - Pulmonary/alveolar hemorrhage
III.a - Alveolar hemorrhage, diffuse (DAH)
IV.a IV - Airway involvement
IV.a - Bronchospasm - Wheezing - Asthma
VI.b VI - Pulmonary vasculopathies
VI.b - Pulmonary arterial hypertension
VII.h VII - Mediastinal involvement
VII.h - Pneumomediastinum (may cause UAO)
VIII.ae VIII - Central-large-upper airway (incl pharyngeal-nasal) involvement
VIII.ae - 'Meth mouth'
IX.ae IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
IX.ae - Stroke
X.m X - Systemic/Distant conditions, syndromes and reactions
X.m - Vascultis (Pulmonary and/or systemic) - ANCA status unknown or negative)
X.u X - Systemic/Distant conditions, syndromes and reactions
X.u - Multiple organ dysfunction/failure (MODS/MOF)
XI.b XI - Miscellaneous
XI.b - Chest pain (acute or subacute), lone or prominent
XI.r XI - Miscellaneous
XI.r - Death following exposure or poisoning
XII.f XII - Cardiovascular involvement / toxicity
XII.f - Cardiomyopathy (acute, subacute, chronic)
XII.g XII - Cardiovascular involvement / toxicity
XII.g - Myocardial ischemia/infarction - Coronary artery disease, acute
XV.q XV - Pathology
XV.q - Path: Foreign body deposits/granulomatous reaction
1

Talc (inhaled, sniffed, i.v., intrapleural)

I.d I - Interstitial/parenchymal lung disease
I.d - Organizing pneumonia pattern (an area or areas of consolidation on imaging)
I.t I - Interstitial/parenchymal lung disease
I.t - Pneumoconiosis (silicosis, talcosis...)
II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
II.f II - Pulmonary edema - Acute lung injury - ARDS
II.f - Hypoxemia, low saturation (may occur in isolation)
IV.c IV - Airway involvement
IV.c - Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)
IV.i IV - Airway involvement
IV.i - Foreign body aspiration bronchiolitis
IV.m IV - Airway involvement
IV.m - Bronchial stenosis/stricture
V.c V - Pleural and/or pericardial involvement
V.c - Pleural thickening
V.r V - Pleural and/or pericardial involvement
V.r - Pleural mass or masses
VI.b VI - Pulmonary vasculopathies
VI.b - Pulmonary arterial hypertension
VI.g VI - Pulmonary vasculopathies
VI.g - Foreign body vasculopathy (Excipient lung disease)
VII.f VII - Mediastinal involvement
VII.f - An enlarged or dense thymus
VII.n VII - Mediastinal involvement
VII.n - Mediastinal talcoma
XI.b XI - Miscellaneous
XI.b - Chest pain (acute or subacute), lone or prominent
XI.u XI - Miscellaneous
XI.u - Chest pressure/discomfort
XV.e XV - Pathology
XV.e - Path: ILD with a granulomatous component (see also Im)
XV.q XV - Pathology
XV.q - Path: Foreign body deposits/granulomatous reaction
XV.s XV - Pathology
XV.s - Path: Pneumoconiosis (silicosis, talcosis, talcoma)
XV.ag XV - Pathology
XV.ag - Path: Foreign body embolism, microangiopathy, vasculopathy
XVI.w XVI - Imaging
XVI.w - Imaging: Lung nodule or nodules
XVI.ae XVI - Imaging
XVI.ae - Imaging: A pattern similar to pneumoconiotic progressive massive fibrosis (PMF)
XVI.bm XVI - Imaging
XVI.bm - Imaging: Avid pleural uptake on PET-scan
XVIII.i XVIII - Distinctive patterns - 'Eye-catchers'
XVIII.i - Eye-catcher: Tracer-avid pleural area or areas on PET-CT
XIX.k XIX - Cytological, biochemical features of/in BAL, pleural fluid or FNA
XIX.k - BAL: Talc crystals in macrophages or lying free in BALF
2